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Neurodegenerative Diseases

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Neurodegenerative Diseases

Targeting Mitochondrial Dysfunction in Neurodegenerative Disease

Some brain disorders are linked to problems with mitochondria, which power cells among other critical functions. Researchers find that improving their function and increasing their numbers might stem some diseases and reduce symptoms of others.
Neurodegenerative Diseases

DNA Repair System Implicated in Brain Disorders, Too

DNA damage and repair are widely studied by cancer biologists and immunologists; now neuroscientists are taking a look.
Neurodegenerative Diseases

It Starts at the Synapse

Report from Neuroscience 2015

New research suggests that neurodegenerative disease, like neurodevelopmental disorders, may actually start with the synapse, the small gap between two neurons in which neurochemical messages are passed.
Neurodegenerative Diseases

Tracking Neuroinflammation in Development, Neurodegenerative Disease

Report from Neuroscience 2014

Researchers use new techniques and drugs to see if inflammation is a cause or an effect of brain illnesses.
Cartoon of axons linking to neuron
Neurodegenerative Diseases

The Promise and the Reality of Stem-Cell Therapies for Neurodegenerative Diseases

Jonathan D. Glass, M.D., is leading a clinical trial testing the safety of using adult stem cells to treat patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that remains untreatable. This trial, along with others like it, is just the beginning of a time-intensive process necessary to determine whether the benefits of stem-cell treatments—if there prove to be any—outweigh the risks. See also Commentary on this article, by Vassilis E. Koliatsos, M.D., and Leyan Xu, M.D., Ph.D.

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