How We Decide: The Neuronal Reward Signal
Using electrophysiologic measures of neuronal activity, we tested theories of reward and decision-making and have found neuronal mechanisms in circuits including dopamine neurons, the striatum, the frontal cortex, and the amygdala that reflect reward and decisions.
Finding Clues to Schizophrenia Outside Neurons
Ariel Y. Deutch, Ph.D. James G. Blakemore Chair of Psychiatry, professor of psychiatry and pharmacology Vanderbilt University Medical Center View article as PDF In 1972 the distinguished neurologist Fred Plum famously labeled efforts to reveal structural changes in the brain in schizophrenia the “graveyard of neuropathologists.” This conclusion came on the heels of research dating […]
Parsing the Puzzle of Parkinson’s GeneticsRecent Findings Reveal Autophagy Malfunction as Common Pathway; Suggest a Roadmap for Early Diagnosis and Intervention
Research into the heritability of Parkinson’s has uncovered novel pathways that could help explain the progressive neuronal degeneration associated with the disease.
A Bayesian Approach to the Brain
Florent Meyniel, Ph.D. Cognitive Neuroimaging Unit, Neurospin, CEA, University Paris-Saclay, France View Article as PDF Bayesian concepts are appealing to many researchers in fundamental and applied research, including neuroscience. Bayesian tools, part of probability theory, are useful whenever quantitative analysis is needed, such as in statistics, data mining, or forecasting. However, Bayesian concepts have much […]