Kevin J. Tracey, M.D.
Kevin J. Tracey, M.D., is president of the Feinstein Institute for Medical Research and Jacobson professor and head of the Laboratory of Biomedical Science. He is a member of the American Society for Clinical Investigation and the Association of American Physicians, and holds a doctorate honoris causa from the Karolinska Institute. He is a neurosurgeon by training, and his laboratory’s contributions to science include discovering HMGB1, a pivotal mediator of sterile and infectious inflammation, and delineating the molecular and neurophysiological basis of neural circuits that control immunity. Dr. Tracey is the author of Fatal Sequence (Dana Press, 2005).
A New Approach to Rheumatoid ArthritisTreating Inflammation with Computerized Nerve Stimulation
Doctors currently treat rheumatoid arthritis, a crippling autoimmune disease, with an arsenal of drugs that, while often effective, can have serious side effects. Authors Ulf Andersson and Kevin J. Tracey describe a circuit between the immune system and the nervous system that enabled development of an implanted nerve stimulator to treat the disorder, now being tested by a patient in Bosnia. If further clinical trials show as much promise as this initial case, similar devices may be developed for a broad range of inflammation-related diseases, from diabetes to congestive heart failure.