Placebo Versus Antidepressant

Review: The Emperor’s New Drugs: Exploding the Antidepressant Myth

Comments

placebo vs antidepressant
Johan Smits

7/14/2010 2:02:19 PM

 Floyd has to read his cited studies more carefully. In the study of sertraline he cites as a good study the conclusion in the abstract is totaly different.A total of 59 studies, mostly of low quality, were included in the review, involving multiple treatment comparisons between sertraline and other antidepressant agents. Evidence favouring sertraline over some other antidepressants for the acute phase treatment of major depression was found, either in terms of efficacy (fluoxetine) or acceptability/tolerability (amitriptyline, imipramine, paroxetine and mirtazapine). However, some differences favouring newer antidepressants in terms of efficacy (mirtazapine) and acceptability (bupropion) were also found. In terms of individual side effects, sertraline was generally associated with a higher rate of participants experiencing diarrhoea.