by Bruce McEwen, Ph.D; Ana C. Pereira, M.D.
Goal: Investigators will conduct an initial clinical study of the drug Riluzole in a small number of adults with mild cognitive impairment to see whether it decreases metabolic changes in the brain that may be associated with progression to Alzheimer...Read more >
by Sheila Blumstein, Ph.D.
This pilot study will explore the potential efficacy of a targeted speech therapy program in improving speech sounds and ultimately communication by patients who developed aphasia as a result of a stroke.
Stroke-induced injuries to the brain can r...Read more >
by Emad Eskandar, M.D.
This neurosurgical research team will explore, at the neuronal level, how two brain networks normally drive the balance between safe and risky decision-making behaviors, and use the findings to design deep brain stimulation (DBS) strategies for modif...Read more >
by Stephan Mayer, M.D.
Investigators will create the capacity to graphically display real-time brain physiologic changes in comatose patients to guide urgent clinical interventions to prevent further damage.
Continuous multimodal monitoring systems that measure and recor...Read more >
by Huntington Potter, Ph.D.
Investigators will undertake the second phase of their clinical study to determine in a small number of people with Alzheimer’s disease whether the drug Leukine shows promise in improving patients’ cognitive abilities and arrests brain atrophy.
Abou...Read more >
by Stanley B. Prusiner, M.D.
Chronic traumatic encephalopathy (CTE) is a progressive degenerative brain disease that results from repetitive “closed” head trauma and produces symptoms that range from problems with attention, concentration, disorientation, and depressio...Read more >
by Dr. Michael Rafii
study of adults
with Down’s syndrome, who have a high probability of
developing mild cognitive impairment that eventually progresses
dementia superimposed on the existing intellectual
disability, may identify biomarker...Read more >
by Dr. Martin M. Monti
Investigators will conduct the first clinical evaluation of the effects of using non-invasive Low Intensity Focused Ultrasound Pulsations to restore consciousness in a small number of severely head-injured adults. Few disorders ar...Read more >
by Guy McKhann, M.D.
This study will continue an
assessment of whether the increased risk of stroke in older patients who
undergo a catheter-based rather than surgical replacement of their aortic valve
is associated with the technique or with their underlying vas...Read more >
by Diego Pizzagalli, Ph.D. and Randy Auerbach, Ph.D.
Investigators will use psychological testing and imaging in teenage girls whose mothers have major depressive disorder to determine whether specific neurological factors predict which of the adolescents will similarly develop depression.
...Read more >
by Sameer Sheth
Neurosurgical researchers will explore how a specific brain network functions as people make decisions. We are constantly making decisions. Often we make them rapidly with nearly imperceptible effort. Other decisions require ...Read more >
by Samuel Cheshier, M.D., Ph.D.
neurosurgeon and neuroradiologist team will determine whether a new
non-invasive MRI imaging technique can reveal innate immune cells’ presence in
deadly brain tumors in children and adults, and can be used to assess responses
to ...Read more >