Yuesheng Li, M.D., Ph.D.
Yuesheng Li, M.D., Ph.D., is Professor and Director of the Hunan Research Institute of Parasitic Diseases-CDC, Yueyang, Hunan Province, the People's Republic of China. He is also a NHMRC Research Fellow in Public Health and Visiting Scientist at The Queensland Institute of Medical Research. Dr Li earned his M.D. from Hunan Medical University, China, in 1975, obtained his Ph.D. from the University of Queensland in 2000, and, in 2005, he received a Howard Hughes Medical Institute International Research Scholarship, the first Chinese scientist to receive this award. He is a physician/scientist and specialist in population health and infectious diseases, who has worked on the immunogenetics, epidemiology, and the control and clinical management of schistosomiasis in China for more than 25 years. He has accumulated vast experience in undertaking longitudinal surveys for identifying patients with chronic and advanced schistosomiasis. He has a particular research interest in understanding the processes involved in the pathology of schistosomiasis and he is a prolific writer, having published more than 100 research papers and review articles. Dr Li's home Institute is situated in Yueyang City, close to the Dongting Lake, a major endemic area for schistosomiasis in China, and it is recognized as one of the main provincial institutes specializing in parasitic diseases in China.
Thomas A. Wynn, Ph.D. is Senior Investigator and Head, Immunopathogenesis Section, Laboratory of Parasitic Diseases (LPD) , National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), in Bethesda, Maryland. He holds a B.A. in Microbiology and a B.S. in Chemistry from Miami University in Ohio (1986), and received his Ph.D. from the Department of Medical Microbiology and Immunology University of Wisconsin Madison Medical School in 1991. Prior to his current position, he was an IRTA Postdoctoral Fellow (1991-1995), Staff Fellow (1995-1997) and Investigator (1997-2001) in the Immunobiology/Immunology and Cell Biology Sections, LPD, NIAID, NIH.
Dr Wynn's research focuses on understanding the molecular and immunological mechanisms regulating the pathogenesis of schistosomiasis and other granulomatous diseases and on developing a more defined and rational approach to new intervention strategies, including vaccine development. He is recognized as one of the most innovative scientists currently working on the pathology of murine and human schistosomiasis. A major emphasis of his research program has been to dissect the contributions of type-1 and type-2-associated cytokines to the pathogenesis of schistosomiasis. Dr Wynn's recent research has exploited microarray analysis to further characterize novel aspects of the Th1/Th2 paradigm in schistosome-induced pathogenesis, and his team is at the forefront of this technology that is exploring the molecular mechanisms involved in fibrogenesis, collagen deposition, granuloma formation, and the progression to hepatosplenic disease.
Donald P. McManus, Ph.D., D.Sc., is Senior Principal Research Fellow and Head of the Molecular Parasitology Laboratory at the Queensland Institute of Medical Research (QIMR) , Brisbane, Australia. He also holds the titles of Professor of Tropical Health, University of Queensland (UQ) and Professor, Griffith University in Brisbane. He obtained his higher degrees from the University of Wales, United Kingdom, and, following academic positions at Imperial College, London, he moved to Brisbane in 1989 to become Research Coordinator of an Australian government-funded Tropical Health Program, a joint consortium between QIMR and THP.
His laboratory focuses on understanding the biology and pathogenesis of parasitic worms of humans, particularly schistosoma bloodflukes and the hydatid (Echinococcus) tapeworms, and on developing new interventions (particularly vaccines) and diagnostic procedures against these pathogens that will aid in their elimination. He has held the position of Vice-President of the World Federation of Parasitologists. He is a member of the Asia-Pacific International Molecular Biology Network, and he has been an appointed member of the WHO Steering Committee on Schistosomiasis since 2000. He sits on the editorial boards of eleven international journals, has received numerous invitations to present his research at national and international fora, and has published more than 340 articles, 2 books, and 17 book chapters in his career to date.